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CVE-2026-54604
OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.
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The vulnerability can be exploited over the network without needing physical access. It is easy for an attacker to exploit this vulnerability. An attacker needs basic access or low-level privileges. No user interaction is needed for the attacker to exploit this vulnerability.
Limited exploitation activity has been observed. Close monitoring and planned remediation are recommended.
The exploit probability is very low. The vulnerability is unlikely to be exploited in the next 30 days.
We did not find any exploit available. Neither in GitHub repositories nor in the Exploit-Database.
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