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CVE-2026-48705

CriticalCVSS 9.3 / 10
Published Nov 5, 2026·Last modified Nov 6, 2026
Affected Components(103)
project-monai/monai
1.2.0rc4
project-monai/monai
0.5.0rc4
project-monai/monai
1.3.1rc3
1 / 35
Description

MONAI (Medical Open Network for AI) is an AI toolkit for health care imaging. Prior to 1.6.1, PydicomReader._get_affine() trusts non-finite values in the DICOM PixelSpacing, ImagePositionPatient, and ImageOrientationPatient fields and composes them into an affine matrix without validation. An unauthenticated attacker who can upload a crafted DICOM to a default MONAILabel deployment can propagate NaN or infinity values through LoadImaged, Spacingd, model inference, and output writing, causing inference failures, persistent datastore poisoning, or geometrically corrupted results. This issue is fixed in version 1.6.1.

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Risk Scores
Base Score
9.3

The vulnerability can be exploited over the network without needing physical access. It is easy for an attacker to exploit this vulnerability. An attacker does not need any special privileges or access rights. No user interaction is needed for the attacker to exploit this vulnerability. The vulnerability can affect other systems as well, not just the initial system. There is a high impact on the integrity of the data. There is a low impact on the availability of the system.

Threat Intelligence
8.5

Exploitation activity has been observed. Apply available patches or mitigations urgently.

EPSS
0.51%

The exploit probability is very low. The vulnerability is unlikely to be exploited in the next 30 days.

Exploit
Not available

We did not find any exploit available. Neither in GitHub repositories nor in the Exploit-Database.

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