Open-Source Security Intelligence

Know every vulnerability
before it knows you.

DevGuard continuously monitors your dependencies and alerts you when CVEs like this one affect your stack — with real-time threat intelligence built for developers.

Search

CVE-2026-31966

MediumCVSS 6.9 / 10
Published Mar 18, 2026·Last modified Apr 10, 2026
Affected Components(0)

No affected components available

Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. As one method of removing redundant data, CRAM uses reference-based compression so that instead of storing the full sequence for each alignment record it stores a location in an external reference sequence along with a list of differences to the reference at that location as a sequence of "features". When decoding CRAM records, the reference data is stored in a char array, and parts matching the alignment record sequence are copied over as necessary. Due to insufficient validation of the feature data series, it was possible to make the cram_decode_seq() function copy data from either before the start, or after the end of the stored reference either into the buffer used to store the output sequence for the cram record, or into the buffer used to build the SAM MD tag. This allowed arbitrary data to be leaked to the calling function. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Risk Scores
Base Score
6.9

The vulnerability can be exploited over the network without needing physical access. It is easy for an attacker to exploit this vulnerability. An attacker does not need any special privileges or access rights. No user interaction is needed for the attacker to exploit this vulnerability.

Threat Intelligence
2.7

Limited exploitation activity has been observed. Close monitoring and planned remediation are recommended.

EPSS
0.52%

The exploit probability is very low. The vulnerability is unlikely to be exploited in the next 30 days.

Exploit
Not available

We did not find any exploit available. Neither in GitHub repositories nor in the Exploit-Database.

Scan your project

Continuously monitor your dependencies and get alerted when vulnerabilities like this one affect your stack.

Checkout DevGuard